Morph is an important fine chemical, which can be used in the preparation of NOBS, OTOS and other rubber vulcanization promoters and antirust agents, preservatives, cleaners, scale remover, pain reliever, local anesthetic, fruit preservative, textile dyeing auxiliaries, etc. It is widely used in rubber, medicine, pesticides, dyes, coatings and other fields.

The main production methods of morpholine are diethanolamine and diethylene glycol. Diethanolamine method is a traditional production method. The raw material needed for diethanolamine must be imported, and the price is expensive, the reaction yield is low, the production cost is high, and the product is no longer competitive. two

Ethylene glycol method IS a NEWLY DEVELOPED MORPHoline production technology in recent years, with diethylene glycol and liquid ammonia as raw materials, the process is simple, the conversion rate is high, the source of diethylene glycol is sufficient, especially ammonia synthesis plant development MORPHoline has more advantages of liquid ammonia and hydrogen, the existing two thirds of domestic factories use this method to produce morpholine.

With the rapid development of our rubber industry, especially tire industry, morpholine production has been stimulated and promoted. Morpholine has become a hot fine chemical product in China, many research institutes have done a lot of research on its synthesis technology, and the construction of morpholine is upsurge in China. At present, the morpholine not only have a great leap in product quantity, quality, synthetic technology is also from the traditional diethanolamine acid encapsulation-dehydration improvement for foreign commonly used diethylene glycol catalyzed hydrogen power network method, and part of the enterprise product quality, raw material consumption has reached the international advanced level, but due to the small and medium-sized enterprises, production technology and product quality is uneven.

At PRESENT DOMESTIC MORPH TOTAL ANNUAL CAPACITY HAS REACHED 8700 TONS, BUT BECAUSE OF TECHNICAL REASONS, AMONG THEM 3 IN PRODUCTION OR semi-PRODUCTION, so the actual output is not big, BUT ALSO imports MANY PRODUCTS EVERY year. According TO STATISTICS, THE TOTAL DEMAND OF MORPHOLINE IN OUR COUNTRY IN 2001 HAS REACHED 7000 ~ 8000 TONS. In RECENT YEARS, WITH THE PROGRESS OF SCIENCE AND TECHNOLOGY, THE NEW USE OF MORPHOLINE HAS BEEN DEVELOPED, SUCH AS NEW PESTICIDES AND PHARMACEUTICAL varieties have been continuously developed AND PRODUCED, ALKYLMORPHOLINE used IN chemical fiber INDUSTRY SOLVENT is in the stage OF research AND development.

Morpholine can be used as raw material to synthesize dozens of drugs, such as pain relievers, local anesthetics, sedatives, respiratory and vascular stimulants. Morpholine is mainly used in the synthesis of morpholine GUANidine, ibuprofen, naproxen, dichloroaniline, sodium phenylacetate, etc. At present, the annual consumption of morpholine in the pharmaceutical industry is about 800 tons. Since these drugs are TRADITIONAL, DEMAND IS unlikely to increase RAPIDLY, AND THE DEMAND FOR MORPHOLINE IS EXPECTED TO BE ABOUT 1100 TONS IN 2005.

Morpholine as metal corrosion inhibitor, mainly used in iron, copper, zinc, lead and other metal corrosion prevention, our country is in the initial stage. In the solvent, surfactant, fluorescent whitening agent, textile additive and catalyst, China also started relatively late.

Morpholine is mainly used as a synthetic rubber curing accelerant (NOBS, OTOS, 26). Among them, mainly used for synthetic NOBS, the 1990s before Europe, America and other developed areas rubber vulcanization promoters consumption accounted for more than 50% of the total demand for morpholine, at present our consumption of more than 30% is used in NOBS. In recent years, international harmful in rubber processing process of nitrosamines toxicity problem is becoming more and more attention of the accelerator, many global restrictive regulations introduced, such as Germany as early as 1982 promulgated regulations control nitrosamines content, the United States, Japan, France, the UK actively developing a new type of vulcanization accelerator does not produce nitrosamines, And stop the use of nitrosamine vulcanization promoters. Therefore, the consumption of morpholine in foreign countries decreased year by year with the prohibition of NOBS. Although there are currently no corresponding regulations to ban the promoter NOBS, China has joined WTO. Due to the entry of a large number of foreign tires, the promoter localization required is also required to be environmentally friendly, and the use of non-toxic promoter to replace NOBS has become an inevitable trend. In recent years, the demand of NOBS is decreasing obviously in our country. According to the National Rubber Additive “Tenth Five-Year Plan”, by 2005, the secondary amine promoters that can decompose nitrosamines will basically not be used in our country. If NOBS is banned and stopped in our country, the production and market of morph will be seriously affected.

According to the present development trend, the consumption of non – rubber additives in 2005 will not exceed 4000 tons of morpholine. Therefore, an oversupply of morpholine will appear, and many countries have already banned toxic promoters, morpholine also appear different degrees of surplus, will not be imported from our country, morpholine development prospects are worrying.

At present, the domestic morph production has been able to meet the market demand, so it is not suitable to build a new device, the existing device should be improved and improve the technology, focusing on improving product quality, reducing costs, to promote the development and application of other downstream products with high quality and low price. The purity of many morpholine products produced by domestic devices is not high, but also leads to the degradation of the quality of promoters, so we should develop high purity pharmaceutical products in the future.

A considerable proportion of morpholine was used for metal corrosion inhibitors abroad, mainly as metal gas antirust agent, to prevent metal from being corroded by atmosphere, and has been widely used in machinery instruments, automobiles, medical instruments and other fields, China just started in this area. The atmospheric metal antirust agents used at home and abroad, dicyclohexylamine nitrite and cyclohexylamine carbonate, have great toxicity to human body and environment, which restricts the promotion and application of gas phase antirust agents. Morpholine, as a metal gas-liquid corrosion inhibitor, has the advantages of low toxicity and has a good development prospect. With the development of petrochemical industry in China, WE will provide high quality and low price raw material for morpholine production, and the price of morpholine will drop accordingly, which will be beneficial to the application of metal corrosion protection. In addition, morpholine can also be used as pH value regulator, gas absorbent, synthetic herbicide and so on. Domestic development and research efforts should be strengthened to promote morpholine consumption.

The new polymer monomer morpholine developed rapidly in recent years abroad is also worthy of attention. Alanyl morpholine is prepared by the reaction of acrylate and morpholine. It is used for the modification of water-based polymers. It has good compatibility with a variety of prepolymers and multi-functional acrylamide. With the deepening of application research, many new specific uses will be developed.